DocumentCode
3403933
Title
Force generation and relaxation at the sarcomere level
Author
Palladino, J.L. ; Noordergraaf, A.
Author_Institution
Cardiovascular Studies Unit, Pennsylvania Univ., Philadelphia, PA, USA
fYear
1988
fDate
4-7 Nov. 1988
Firstpage
238
Abstract
Sarcomeres are modeled by parallel and series arrangements of thick (myosin) and thin (actin) filaments whose masses are considered. Contractile force is generated by viscoelastic crossbridge bonds which link the filaments. If bond formation is not perfectly synchronous throughout the sarcomere, small movements of thick with respect to thin filaments result. Such movements lead to bond detachment hence muscle relaxation is proposed to be a mechanism intrinsic to muscle structure and activation mode.<>
Keywords
biomechanics; muscle; physiological models; actin; contractile force; force generation; force relaxation; muscle activation mode; muscle structure; myosin; sarcomeres; viscoelastic crossbridge bonds;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society, 1988. Proceedings of the Annual International Conference of the IEEE
Conference_Location
New Orleans, LA, USA
Print_ISBN
0-7803-0785-2
Type
conf
DOI
10.1109/IEMBS.1988.94496
Filename
94496
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