Title :
Localizing time-varying periodicities in symbolic sequences
Author :
Arora, Raman ; Sethares, William A. ; Bucklew, James A.
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of Wisconsin-Madison, Madison, WI
fDate :
March 31 2008-April 4 2008
Abstract :
A novel approach is presented for the detection and localization of changing periodicities in symbolic sequences. Various symbolic sequences like DNA can be modelled as stochastic processes that exhibit time-varying cyclostation- arity. The coding regions of the DNA, for instance, exhibit statistical periodicity with period three. The complexity-regularized maximum-likelihood estimates are developed in this paper for the statistical period of symbolic sequences. The changing periodicities along the sequence are discovered by using sliding windows. A cumulative sum test is also presented to detect the change points. The formulation in this paper avoids any kind of numerical mapping for the symbolic DNA sequences and does not impose any algebraic structure.
Keywords :
DNA; biology computing; maximum likelihood sequence estimation; molecular biophysics; stochastic processes; time series; time-varying systems; DNA; complexity-regularized maximum-likelihood estimates; cumulative sum test; sliding windows; stochastic processes; symbolic sequences; time-varying cyclostation- arity; time-varying periodicities; Algebra; DNA; Drives; Maximum likelihood detection; Maximum likelihood estimation; Proteins; Random variables; Sequences; Stochastic processes; Testing; Symbolic periodicity; cyclostationarity; finding exons;
Conference_Titel :
Acoustics, Speech and Signal Processing, 2008. ICASSP 2008. IEEE International Conference on
Conference_Location :
Las Vegas, NV
Print_ISBN :
978-1-4244-1483-3
Electronic_ISBN :
1520-6149
DOI :
10.1109/ICASSP.2008.4517691