Clinical applications of diffuse reflectance spectroscopy in normal and prediabetic subjects-A pilot study

Author

Anand, Sruthy ; Sujatha, N. ; Narayanamurthy, V.B. ; Seshadri, Vivek ; Poddar, Raju

Author_Institution

Dept. of Appl. Mech., Biomed. Eng. Group, Indian Inst. of Technol. Madras, Chennai, India

fYear

2011

fDate

3-5 Aug. 2011

Firstpage

1

Lastpage

4

Abstract

A pilot study was conducted in 4 different regions on the foot sole of normal and prediabetic subjects to determine the ratios of oxy and deoxy hemoglobin bands using diffuse reflectance spectroscopy in visible range. The reflectance spectra of normal subjects showed a greater absorption dips at 542 nm. In conclusion the ratio of R542/R555, ratio of oxy and deoxy hemoglobin bands would be helpful in characterizing tissue oxygenation levels in normal and prediabetic subjects.

Keywords

bio-optics; biochemistry; biological tissues; biomedical measurement; blood; paediatrics; visible spectroscopy; diffuse reflectance spectroscopy clinical applications; foot sole; normal subjects; oxyhemoglobin-deoxyhemoglobin band ratio; prediabetic subjects; reflectance spectra; tissue oxygenation levels; wavelength 542 nm; wavelength 555 nm; Diabetes; Foot; Joints; Optical reflection; Spectroscopy; Wounds; diabetic foot ulcers; diffuse reflectance spectroscopy; in vivo diagnosis;

fLanguage

English

Publisher

ieee

Conference_Titel

Defense Science Research Conference and Expo (DSR), 2011

Conference_Location

Singapore

Print_ISBN

978-1-4244-9276-3

Type

conf

DOI

10.1109/DSR.2011.6026804

Filename

6026804