Title :
Clinical applications of diffuse reflectance spectroscopy in normal and prediabetic subjects-A pilot study
Author :
Anand, Sruthy ; Sujatha, N. ; Narayanamurthy, V.B. ; Seshadri, Vivek ; Poddar, Raju
Author_Institution :
Dept. of Appl. Mech., Biomed. Eng. Group, Indian Inst. of Technol. Madras, Chennai, India
Abstract :
A pilot study was conducted in 4 different regions on the foot sole of normal and prediabetic subjects to determine the ratios of oxy and deoxy hemoglobin bands using diffuse reflectance spectroscopy in visible range. The reflectance spectra of normal subjects showed a greater absorption dips at 542 nm. In conclusion the ratio of R542/R555, ratio of oxy and deoxy hemoglobin bands would be helpful in characterizing tissue oxygenation levels in normal and prediabetic subjects.
Keywords :
bio-optics; biochemistry; biological tissues; biomedical measurement; blood; paediatrics; visible spectroscopy; diffuse reflectance spectroscopy clinical applications; foot sole; normal subjects; oxyhemoglobin-deoxyhemoglobin band ratio; prediabetic subjects; reflectance spectra; tissue oxygenation levels; wavelength 542 nm; wavelength 555 nm; Diabetes; Foot; Joints; Optical reflection; Spectroscopy; Wounds; diabetic foot ulcers; diffuse reflectance spectroscopy; in vivo diagnosis;
Conference_Titel :
Defense Science Research Conference and Expo (DSR), 2011
Conference_Location :
Singapore
Print_ISBN :
978-1-4244-9276-3
DOI :
10.1109/DSR.2011.6026804
