• DocumentCode
    3412629
  • Title

    Automated DNA sequencing and construction of consensus sequence

  • Author

    Danckaert, Anne ; Hazout, Serge ; Valleron, Alain-Jacques

  • Author_Institution
    INSERM, Paris, France
  • fYear
    1988
  • fDate
    4-7 Nov. 1988
  • Firstpage
    364
  • Abstract
    A novel image processing method called morphological automation, associated with an integrated device (gel swallowing), is proposed to automate the reading of DNA electrophoretic gels. It has been evaluated on the Mason-Pfizer-Monkey virus sequence. Up to 96.6% of the bases were found to be identical to the published sequence. Another algorithm permits reconstruction the entire DNA sequence.<>
  • Keywords
    DNA; biology computing; computerised pattern recognition; computerised picture processing; molecular biophysics; DNA construction; DNA sequencing; Mason-Pfizer-Monkey virus sequence; algorithm; consensus sequence; electrophoretic gels; gel swallowing; image processing method; morphological automation;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 1988. Proceedings of the Annual International Conference of the IEEE
  • Conference_Location
    New Orleans, LA, USA
  • Print_ISBN
    0-7803-0785-2
  • Type

    conf

  • DOI
    10.1109/IEMBS.1988.94560
  • Filename
    94560