Title :
A MOSFET bridge fluid biosensor
Author :
Sellami, Louiza ; Newcomb, Robert W.
Author_Institution :
Dept. of Electr. Eng., U.S. Naval Acad., Annapolis, MD, USA
Abstract :
This paper presents a MOSFET based biosensor circuit for the monitoring of such things as creatinine in patients with renal failure. Its VLSI layout is presented for 1.2 μ or for 2.0 μ MOSIS CMOS processes. The proposed biosensor circuit is a capacitive gap sensor where the device consists of a bridge made of three standard PMOS devices connected either as resistors or capacitors and forming three arms of the bridge. The fourth arm is a similar PMOS transistor but with a gap between the channel and a raised poly layer in which a fluid, such as creatinine, or a gas, can be placed. PSpice simulations and Spice extractions from the layout are included to demonstrate the operation of the circuit
Keywords :
SPICE; VLSI; biomedical electronics; biosensors; bridge circuits; capacitive sensors; kidney; patient monitoring; permittivity; 1.2 micron; 2.0 micron; MOSFET bridge; MOSIS CMOS processes; PSpice simulations; Spice extractions; VLSI layout; capacitive gap sensor; creatinine; fluid biosensor; patient monitoring; raised poly layer; renal failure; standard PMOS devices; Biosensors; Bridge circuits; CMOS process; Capacitive sensors; Condition monitoring; MOS devices; MOSFET circuits; Patient monitoring; Resistors; Very large scale integration;
Conference_Titel :
Circuits and Systems, 1999. ISCAS '99. Proceedings of the 1999 IEEE International Symposium on
Conference_Location :
Orlando, FL
Print_ISBN :
0-7803-5471-0
DOI :
10.1109/ISCAS.1999.777530
