Title :
Intraoperative microelectrode recordings from deep brain structures
Author :
Dostrovsky, J.O.
Author_Institution :
Dept. of Physiol., Univ. of Toronto, & Toronto Western Res. Inst., Toronto, Ont., Canada
Abstract :
My presentation will review the rationale for and methods used to obtain microelectrode recordings of neuronal activity and deliver electrical stimuli through microelectrodes in the brain of awake patients during functional stereotactic neurosurgery performed to make a lesion or implant chronic deep brain stimulation electrodes. I will then describe the types of physiological data that are typically obtained in order to determine the location of the target site. Finally, I will provide examples of some of the types of analysis we have performed from data obtained intraoperatively. These include analysis of firing patterns of single units and pairs of units, and spectral and coherence analysis.
Keywords :
bioelectric potentials; biomedical electrodes; brain; medical signal processing; microelectrodes; neurophysiology; spectral analysis; surgery; action potentials; awake patients; coherence analysis; deep brain structures; electrical stimuli; firing patterns; functional stereotactic neurosurgery; intraoperative microelectrode recordings; local field potentials; neuronal activity; oscillatory activity; pairs of units; sensory evoked potentials; single units; spectral analysis; Anesthesia; Brain stimulation; Electrodes; Lesions; Microelectrodes; Neurosurgery; Pattern analysis; Physiology; Satellite broadcasting; Spectral analysis;
Conference_Titel :
Neural Engineering, 2003. Conference Proceedings. First International IEEE EMBS Conference on
Print_ISBN :
0-7803-7579-3
DOI :
10.1109/CNE.2003.1196866
