Title :
A world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber micro PCR chip
Author :
Oh, Kwang W. ; Park, Chinsung ; Kak Namkoong
Author_Institution :
Bio Lab, Samsung Adv. Inst. of Technol., Suwon, South Korea
fDate :
30 Jan.-3 Feb. 2005
Abstract :
This paper presents a practical world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber Micro PCR (Polymerase Chain Reaction) chip. After sample injection and sealing, leakage test is conducted by elevating the temperature up to 100 °C for 30 min. No leakage flows are found during the test for 10 cartridges. In conclusion, we have introduced a simple and cheap microfluidic interconnection technology for both sample injection and sealing, which provides a zero dead volume, a zero leakage flow, and biochemical compatibility. Also, this world-to-chip interconnection technology enables one or more operators to interface between the micro world and real world easily by using conventional pipettes.
Keywords :
biochemistry; biological techniques; leak detection; microfluidics; seals (stoppers); 100 C; 30 min; biochemical compatibility; leakage test; multichamber micro PCR chip; pipettes; polymerase chain reaction chip; sample injection; sealing; world-to-chip microfluidic interconnection technology; zero leakage flow; Biomedical optical imaging; Chemical technology; Commercialization; Fluidic microsystems; Microfluidics; Microvalves; Temperature; Testing; Valves; Vents;
Conference_Titel :
Micro Electro Mechanical Systems, 2005. MEMS 2005. 18th IEEE International Conference on
Print_ISBN :
0-7803-8732-5
DOI :
10.1109/MEMSYS.2005.1454029