Title :
A novel nano power biosensor for real time monitoring of creatinase and urease in peritoneal dialysis
Author :
Premanode, Bhusana ; Toumazou, Christofer
Author_Institution :
Dept. of Bioeng., Imperial Coll., London, UK
Abstract :
A novel biosensor based on immobilized creatininase, creatinase and urease as sensitive elements at the 6-8 pH and 37.0°C; using ISFETs operating in weak inversion is proposed. Results demonstrate linear characteristics of the urea and creatinine at the range of 0-200 mM and 0-2000 μM with the sensor´s power consumption in the nanoamp region. Such characteristics fit the analytical requirements to improving real time peritoneal dialysis (PD).
Keywords :
biochemistry; biosensors; enzymes; ion sensitive field effect transistors; kidney; molecular biophysics; nanotechnology; patient monitoring; patient treatment; 37.0 degC; ISFETs; creatinase; creatininase; nano power biosensor; peritoneal dialysis; real time monitoring; urease; Biochemistry; Biomedical engineering; Biomedical monitoring; Biosensors; Catheters; Diseases; Educational institutions; FETs; Temperature sensors; Timing;
Conference_Titel :
Biomedical Circuits and Systems, 2004 IEEE International Workshop on
Print_ISBN :
0-7803-8665-5
DOI :
10.1109/BIOCAS.2004.1454142
