• DocumentCode
    34333
  • Title

    An Odd Parity Checker Prototype Using DNAzyme Finite State Machine

  • Author

    Eshra, Abeer ; El-Sayed, Ayman

  • Author_Institution
    Dept. of Comput. Sci. & Eng., Menoufia Univ., Menouf, Egypt
  • Volume
    11
  • Issue
    2
  • fYear
    2014
  • fDate
    March-April 2014
  • Firstpage
    316
  • Lastpage
    324
  • Abstract
    A finite-state machine (FSM) is an abstract mathematical model of computation used to design both computer programs and sequential logic circuits. Considered as an abstract model of computation, FSM is weak; it has less computational power than some other models of computation such as the Turing machine. This paper discusses the finite-state automata based on Deoxyribonucleic Acid (DNA) and different implementations of DNA FSMs. Moreover, a comparison was made to clarify the advantages and disadvantages of each kind of presented DNA FSMS. Since it is a major goal for nanoscince, nanotechnology and super molecular chemistry is to design synthetic molecular devices that are programmable and run autonomously. Programmable means that the behavior of the device can be modified without redesigning the whole structure. Autonomous means that it runs without externally mediated change to the work cycle. In this paper we present an odd Parity Checker Prototype Using DNAzyme FSM. Our paper makes use of a known design for a DNA nanorobotic device due to Reif and Sahu for executing FSM computations using DNAzymes. The main contribution of our paper is a description of how to program that device to do a FSM computation known as odd parity checking. We describe in detail finite state automaton built on 10-23 DNAzyme, and give its procedure of design and computation. The design procedure has two major phases: designing the language potential alphabet DNA strands, and depending on the first phase to design the DNAzyme possible transitions.
  • Keywords
    DNA; biochemistry; biocontrol; biological techniques; biology computing; enzymes; nanobiotechnology; parity; robots; DNA nanorobotic device; DNAzyme FSM; DNAzyme finite state machine; DNAzyme transitions; DNAzymes; Deoxyribonucleic Acid; FSM computation; Reif; Sahu; Turing machine; abstract mathematical model; autonomous; computation procedure; computational power; computer programs; design procedure; device behavior; finite-state automata; finite-state machine; language potential alphabet DNA strands; nanoscince; nanotechnology; odd parity checker prototype; sequential logic circuits; super molecular chemistry; synthetic molecular device design; Biochemistry; Computational modeling; Computers; DNA; Nanobioscience; Turing machines; DNA computing; DNAzymes; Finite state automata; restriction enzymes;
  • fLanguage
    English
  • Journal_Title
    Computational Biology and Bioinformatics, IEEE/ACM Transactions on
  • Publisher
    ieee
  • ISSN
    1545-5963
  • Type

    jour

  • DOI
    10.1109/TCBB.2013.2295803
  • Filename
    6690110