DocumentCode
34333
Title
An Odd Parity Checker Prototype Using DNAzyme Finite State Machine
Author
Eshra, Abeer ; El-Sayed, Ayman
Author_Institution
Dept. of Comput. Sci. & Eng., Menoufia Univ., Menouf, Egypt
Volume
11
Issue
2
fYear
2014
fDate
March-April 2014
Firstpage
316
Lastpage
324
Abstract
A finite-state machine (FSM) is an abstract mathematical model of computation used to design both computer programs and sequential logic circuits. Considered as an abstract model of computation, FSM is weak; it has less computational power than some other models of computation such as the Turing machine. This paper discusses the finite-state automata based on Deoxyribonucleic Acid (DNA) and different implementations of DNA FSMs. Moreover, a comparison was made to clarify the advantages and disadvantages of each kind of presented DNA FSMS. Since it is a major goal for nanoscince, nanotechnology and super molecular chemistry is to design synthetic molecular devices that are programmable and run autonomously. Programmable means that the behavior of the device can be modified without redesigning the whole structure. Autonomous means that it runs without externally mediated change to the work cycle. In this paper we present an odd Parity Checker Prototype Using DNAzyme FSM. Our paper makes use of a known design for a DNA nanorobotic device due to Reif and Sahu for executing FSM computations using DNAzymes. The main contribution of our paper is a description of how to program that device to do a FSM computation known as odd parity checking. We describe in detail finite state automaton built on 10-23 DNAzyme, and give its procedure of design and computation. The design procedure has two major phases: designing the language potential alphabet DNA strands, and depending on the first phase to design the DNAzyme possible transitions.
Keywords
DNA; biochemistry; biocontrol; biological techniques; biology computing; enzymes; nanobiotechnology; parity; robots; DNA nanorobotic device; DNAzyme FSM; DNAzyme finite state machine; DNAzyme transitions; DNAzymes; Deoxyribonucleic Acid; FSM computation; Reif; Sahu; Turing machine; abstract mathematical model; autonomous; computation procedure; computational power; computer programs; design procedure; device behavior; finite-state automata; finite-state machine; language potential alphabet DNA strands; nanoscince; nanotechnology; odd parity checker prototype; sequential logic circuits; super molecular chemistry; synthetic molecular device design; Biochemistry; Computational modeling; Computers; DNA; Nanobioscience; Turing machines; DNA computing; DNAzymes; Finite state automata; restriction enzymes;
fLanguage
English
Journal_Title
Computational Biology and Bioinformatics, IEEE/ACM Transactions on
Publisher
ieee
ISSN
1545-5963
Type
jour
DOI
10.1109/TCBB.2013.2295803
Filename
6690110
Link To Document