Title :
Noncontact transportation of DNA molecule by dielectrophoretic force
Author :
Morishima, Keisuke ; Fukuda, Toshio ; Arai, Fumihito ; Ishihara, Hidenori ; Matsuura, Hideo ; Yoshikawa, Kenichi
Author_Institution :
Dept. of Micro Syst. Eng., Nagoya Univ., Japan
Abstract :
In this paper, we propose a new approach to noncontact transportation of DNA molecules by dielectrophoretic force and the idea of the Micro DNA Flow System. Such systems can be made by using microfabrication technology. At first, we designed a simple micro electrode-flow system and carried out experiments. Experimental demonstration of DNA transportation using dielectrophoretic force and direct observation of the DNA molecule in a non-uniform electric field was carried out with fluorescence microscopy. Motion of the DNA molecule is modeled in terms of the electric field generated by the electrode design. We compared the experimental results with the motion of the DNA molecule which is theoretically predicted. We showed a simple electrode design and the possibility of noncontact transportation of DNA molecules based on Micro DNA Flow System
Keywords :
DNA; biological fluid dynamics; biological techniques; electrophoresis; gels; microelectrodes; molecular biophysics; physiological models; DNA molecule; Micro DNA Flow System; dielectrophoretic force; electrode design; fluorescence microscopy; micro electrode-flow system; noncontact transportation; nonuniform electric field; Bioinformatics; Biological cells; DNA; Dielectrophoresis; Electrodes; Electrokinetics; Genomics; Humans; Microelectrodes; Transportation;
Conference_Titel :
Micro Machine and Human Science, 1995. MHS '95., Proceedings of the Sixth International Symposium on
Conference_Location :
Nagoya
Print_ISBN :
0-7803-2676-8
DOI :
10.1109/MHS.1995.494231
