Title :
Photolithography as a tool to fabricate polymeric flow chambers for in-vitro cellular applications
Author :
Bucaro, Michael A. ; Calvert, Jeffrey M. ; Rudolph, Alan S. ; Spargo, Barry ; Kapur, Dr Ravi
Author_Institution :
Sch. of Eng. & Appl. Sci., Virginia Univ., Charlottesville, VA, USA
Abstract :
A modified photolithographic approach to fabricating optically clear, 10 μm and above wide multiple channels in biomedically relevant polymers like poly(dimethyl-siloxalane) is described. This approach allows control of size and shape of the channels and vessel wall architecture. Elimination of wet etchants, such as hydrofluoric acid, enables better control on the chemistry and surface topography of the formed channels
Keywords :
biological techniques; cellular biophysics; photolithography; polymers; 10 mum; HF; biomedically relevant polymers; in-vitro cellular applications; modified photolithographic approach; optically clear multiple channels fabrication; poly(dimethyl-siloxalane); polymeric flow chambers fabrication; surface topography; vessel wall architecture; wet etchants; Biomedical engineering; Cells (biology); Fabrication; Geometry; Glass; In vitro; Laboratories; Lithography; Optical polymers; Shape control;
Conference_Titel :
Biomedical Engineering Conference, 1997., Proceedings of the 1997 Sixteenth Southern
Conference_Location :
Biloxi, MS
Print_ISBN :
0-7803-3869-3
DOI :
10.1109/SBEC.1997.583259
