Title :
Endoscopic optical coherence tomography: clinical applications and functional extensions
Author :
Rollins, A.M. ; Westphal, V. ; Horii, A. ; Sivak, M.V. ; Chak, A. ; Das, Aruneema ; Wong, R.C.K. ; Izatt, Joseph A.
Author_Institution :
Departments of Medicine & Biomed. Eng., Case Western Reserve Univ., Cleveland, OH, USA
Abstract :
Summary form only given. Optical coherence tomography (OCT) is an emerging biomedical imaging technique that uses low-coherence optical interferometry to obtain micron-scale resolution cross-sectional images of tissue microstructure non-invasively. OCT fills a valuable niche in imaging of tissue structure, providing subsurface imaging with high spatial resolution (on the order of 10 micrometers) and penetration depths of 1-2 mm with no contact or matching medium needed between the probe and the tissue. We have developed an OCT system for gastrointestinal (GI) endoscopy using a small-diameter rotary-scanning probe compatible with standard GI endoscopes and capable of imaging in real-time.
Keywords :
biological organs; biomedical equipment; biomedical imaging; light interferometry; optical tomography; Barrett´s esophagus; biomedical imaging; clinical applications; cross-sectional images; early cancer detection; endoscopic optical coherence tomography; functional extensions; gastrointestinal endoscopy; gastrointestinal organs; high spatial resolution; low-coherence optical interferometry; neoplastic lesions; real-time imaging; second-generation prototypes; small-diameter rotary-scanning probe; subsurface imaging; tissue microstructure; tumor margins; Biomedical imaging; Biomedical optical imaging; Endoscopes; High-resolution imaging; Image resolution; Optical imaging; Optical interferometry; Probes; Spatial resolution; Tomography;
Conference_Titel :
Lasers and Electro-Optics, 2001. CLEO '01. Technical Digest. Summaries of papers presented at the Conference on
Conference_Location :
Baltimore, MD, USA
Print_ISBN :
1-55752-662-1
DOI :
10.1109/CLEO.2001.947766
