Microfluidic synthesis of fluorescent magnetonanoparticles and characterization

This study presents a stable and controllable synthesis of the fluorescent magnetic nanoparticles in a flow-through microchannel. La Mer process is carried out to synthesize the magnetic nanoparticles using co-precipitation. Then, the magnetic nanoparticles are coated with conjugation of chitosan and fluorescent isothiocianate. The chemical composition of the magnetic nanoparticles and their sizes are determined. The magnetic property of saturation magnetization and coercive field is characterized. Also, the possibility of external manipulation by separating the synthesized fluorescent magnetic nanoparticles into non-reacting lamination flow is demonstrated. Finally, their fluorescence property is determined.