Two Dimensional Modeling and Fractal Characterization of Tumor Vascular Network

Author

Dobrescu, Radu ; Ichim, Loretta

Author_Institution

Fac. of Autom. Control & Comput., Politeh. Univ. of Bucharest, Bucharest, Romania

fYear

2009

fDate

3-5 Aug. 2009

Firstpage

483

Lastpage

486

Abstract

Tumor networks display percolation like scaling, representing the first evidence for a biological growth process whose key determinants are local substrate properties. In this paper we present a full characterization of a recently proposed model which reproduces the main features of the biological system, focusing on its dynamical properties, on the fractal properties of patterns, and on the percolative phase transition. We propose a simple model which reproduces many features of the biological system.

Keywords

blood vessels; cancer; fractals; medical computing; percolation; physiological models; tumours; biological growth process; computer-aided model; fractal characterization; invasion percolation; percolative phase transition; tumor growth; tumor vascular network; two dimensional modeling; Bioinformatics; Biological system modeling; Biological systems; Biology computing; Computational modeling; Computer networks; Context modeling; Fractals; Mathematical model; Neoplasms; computational modeling; fractal dimension; invasion percolation; tumor growth; two-dimensional; vascular network;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics, Systems Biology and Intelligent Computing, 2009. IJCBS '09. International Joint Conference on

Conference_Location

Shanghai

Print_ISBN

978-0-7695-3739-9

Type

conf

DOI

10.1109/IJCBS.2009.71

Filename

5260425