An inverse method for hyperthermia phased-array pattern synthesis

A novel method for computing array element amplitude and phase-driving distributions for direct synthesis of multiple-focus field patterns using ultrasonic phase arrays is shown to be capable of producing desired field levels at a set of control points in the treatment volume. The complex pressure at any of these control points can be chosen to produce the desired power deposition at that point, including reducing the field level to avoid potential hot spots, providing a powerful tool for hyperthermia treatment planning. The method also allows the complex excitation vector to be weighted to reduce the dynamic range of the driving signals without disturbing the relative field levels at the control points, allowing near maximum power transfer from the array into the treatment volume