Title :
A low noise bandpass neuro-amplifier with adjustable bandwidth for bio-medical applications
Author :
Liu, Cheng C. ; Chang, Jian ; Yuan, Sitong ; Johnson, Louis G. ; Rennaker, Robert L.
Author_Institution :
Eng. & Technol. Dept., Univ. of Wisconsin - Stout, Menomonie, WI, USA
Abstract :
This paper presents a design and experimental results of a bio-potential amplifier design with a noise filtering capability. The amplifier is operated in the subthreshold region for micro-volt neuron signal sensing, amplification, and filtering. The amplification provides 10 K-Hz bandwidth with tunable cutoff sensing frequencies from 0 Hz to 500 Hz and 6KHz to 10 KHz adjustable range at high frequencies. The amplifier is experimentally validated and was fabricated using a 0.35 um 2P4M mixed-signal polycide process, and has a 70 dB pass-band gain, and 105 uVrms measured noise at negligible load and 88 uVrms with a 2pF active probe loading. The performance characteristics of bio-potential recording amplifiers are compared with the proposed design. The proposed design has reduced the bio-potential amplifier complexity significantly due to the tunnable pico-amphere feedback network but with the cost of increased input referred noise for transistors operated in the subthreshold region.
Keywords :
band-pass filters; biomedical electronics; feedback; low noise amplifiers; biomedical applications; biopotential recording amplifiers; frequency 0 Hz to 500 Hz; frequency 6 kHz to 10 kHz; low noise bandpass neuro-amplifier; microvolt neuron signal sensing; mixed-signal polycide process; noise filtering; picoamphere feedback network; Active noise reduction; Band pass filters; Bandwidth; Costs; Cutoff frequency; Filtering; Gain measurement; Neurons; Noise measurement; Probes;
Conference_Titel :
Green Circuits and Systems (ICGCS), 2010 International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-6876-8
Electronic_ISBN :
978-1-4244-6877-5
DOI :
10.1109/ICGCS.2010.5543024
