[Front cover]

The following topics are dealt with: metabolite biomarker discovery; metabolic diseases; flux analysis; alternating weighted least squares parameter estimation; biological S-systems; drug therapy; time series gene expression; protein-protein interaction network; basin structure; Boolean networks; long range correlated dynamics; human encoded miRNAs; influenza virus genome; three weighted human gene functional association networks; cell renal cell carcinoma; human tissue specific genes; protein phosphorylation sites; functional tunability; fixed-point blind source extraction algorithm; ECG data analysis; human diseases; diabetes progression; HBV infection models; network kernel SVM; microarray classification; gene sets selection; machine learning framework; metagenomic data; and combinatorial gene regulation networks.