Title :
An Artificial Immune System for Temporal Anomaly Detection Using Cell Activation Thresholds and Clonal Size Regulation with Homeostasis
Author :
Antunes, Mário J. ; Correia, Manuel E.
Author_Institution :
Polytech. Inst. of Leiria (ESTG/DEI), Leiria, Portugal
Abstract :
This paper presents an artificial immune system (AIS) based on Grossman´s tunable activation threshold (TAT) for anomaly detection. We describe the immunological metaphor and the algorithm adopted for T-cells, emphasizing two important features: the temporal dynamic adjustment of T-cells clonal size and its associated homeostasis mechanism. We present some promising results obtained with artificially generated data sets, aiming to test the appropriateness of using TAT in dynamic changing environments, to distinguish new unseen patterns as part of what should be detected as normal or as anomalous.
Keywords :
biological techniques; cellular biophysics; Grossman´s tunable activation threshold; T-cells; artificial immune system; cell activation thresholds; clonal size regulation; homeostasis; immunological metaphor; temporal anomaly detection; temporal dynamic adjustment; Artificial immune systems; Artificial intelligence; Bioinformatics; Biology computing; Home computing; Immune system; Intelligent systems; Pathogens; Peptides; Systems biology; Artificial Immune System; anomaly detection; clonal size control; homeostasis; tunable activation threshold;
Conference_Titel :
Bioinformatics, Systems Biology and Intelligent Computing, 2009. IJCBS '09. International Joint Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-0-7695-3739-9
DOI :
10.1109/IJCBS.2009.59