DocumentCode :
3461720
Title :
A high resolution PET for animal studies
Author :
Watanabe, M. ; Uchida, H. ; Okada, H. ; Shimizu, K. ; Satoh, N. ; Yoshikawa, E. ; Ohmura, T. ; Yamashita, T. ; Tanaka, E.
Author_Institution :
Hamamatsu Photonics K.K., Hamakita, Japan
fYear :
1991
fDate :
2-9 Nov. 1991
Firstpage :
1648
Abstract :
A high-resolution positron emission tomography (PET) system for in vivo animal studies was developed. A block detector, which is a position-sensitive photomultiplier tube (Hamamatsu R3941-02) coupled to four arrays of 1.7-mm-wide BGO crystals, was used. There are 15 block detectors positioned to form a 35-cm-diameter ring, with the coupling of four BGO arrays to each photomultiplier tube. This provides four detector rings, giving the system a seven-slice imaging capability. The gantry head tilts up to +or-90 degrees and is capable of moving up and down by 30 cm. These positioning capabilities allow flexibility and ease of use in subject positioning. A gantry entrance of 22 cm in diameter allows studies ranging from rats and mice to primates such as rhesus and squirrel monkeys. The physical performance of the system was evaluated. The spatial resolution in the center of the field of view (FOV) is 3.0 mm at full width at half maximum (FWHM) in the transaxial plane. The axial resolution at the center of the FOV is 4.8 mm FWHM in the direct plane and 4.1 mm FWHM in the cross plane. The total system sensitivity is 20.7 kcps/ mu Si/ml for a 10-cm-diameter cylindrical uniform phantom with a energy threshold of 300 keV.<>
Keywords :
biological techniques and instruments; computerised tomography; radioisotope scanning and imaging; 1.7 mm; 10 cm; 22 cm; 300 keV; 35 cm; 7-slice imaging; BGO arrays; BGO crystals; Hamamatsu R3941-02; animal studies; axial resolution; biological research instrumentation; block detector; cylindrical uniform phantom; energy threshold; full width at half maximum; gantry head; high resolution PET; mice; position-sensitive photomultiplier tube; positron emission tomography; primates; rats; rhesus monkeys; squirrel monkeys; system sensitivity; transaxial plane; Animals; Crystals; Head; In vivo; Photomultipliers; Position sensitive particle detectors; Positron emission tomography; Rats; Sensor arrays; Spatial resolution;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Nuclear Science Symposium and Medical Imaging Conference, 1991., Conference Record of the 1991 IEEE
Conference_Location :
Santa Fe, NM, USA
Print_ISBN :
0-7803-0513-2
Type :
conf
DOI :
10.1109/NSSMIC.1991.259194
Filename :
259194
Link To Document :
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