Title :
PET imaging of implanted radiotherapy ion beams to monitor and optimise dose delivery to tumor sites
Author :
Litzenberg, D. ; Becchetti, F.D. ; Brown, J.A. ; Roberts, David A. ; Ronningen, R.M. ; Hutchins, G. ; Caraher, J. ; Smith, Ross ; Lamkin, K.A. ; Martin, A.
Author_Institution :
Dept. of Phys., Michigan Univ., Ann Arbor, MI, USA
Abstract :
A secondary, focused beam of /sup 18/F developed at the NSCL (National Superconducting Cyclotron Laboratory), E/A=20 MeV/u, was implanted into a foil-stack phantom. The radioactivity ( beta /sup +/, T/sub 1/2/=110 m) of the stopped beam was imaged at the University of Michigan Positron Emission Tomography (PET) facility using a multiring PET scanner. The possibility of accurately localizing the dose of radiotherapy beams in tumors and obtaining quantitative information on the distribution of stopped beams using a commercial PET scanner was verified. Further work using light-ion (protons in particular) and other beams is in progress, and some preliminary results are reported.<>
Keywords :
computerised tomography; dosimetry; radiation therapy; radioisotope scanning and imaging; /sup 18/F; National Superconducting Cyclotron Laboratory; PET imaging; dose delivery monitoring; dose delivery optimisation; foil-stack phantom; implanted radiotherapy ion beams; light-ion beams; multiring PET scanner; nuclear medicine; radioactivity; stopped beam; tumor sites; Cyclotrons; Focusing; Imaging phantoms; Ion beams; Laboratories; Monitoring; Neoplasms; Particle beams; Positron emission tomography; Protons;
Conference_Titel :
Nuclear Science Symposium and Medical Imaging Conference, 1991., Conference Record of the 1991 IEEE
Conference_Location :
Santa Fe, NM, USA
Print_ISBN :
0-7803-0513-2
DOI :
10.1109/NSSMIC.1991.259200
