Title :
Velocity estimation of mobile single molecules for improved position accuracy
Author :
Yuce, M.Y. ; Erdogan, Alper T. ; Kiraz, A.
Author_Institution :
Phys. Dept., Koc Univ., İstanbul, Turkey
Abstract :
Imaging of single molecules has been modeled as a non-homogenous Poisson process. Model parameters including molecule´s velocity are estimated from individual frames with maximum likelihood estimation. Velocity information is shown to improve the position accuracy.
Keywords :
fluorescence; maximum likelihood estimation; optical images; optical microscopy; stochastic processes; fluorescence microscopy; maximum likelihood estimation; mobile single molecular imaging; model parameters; molecule velocity; nonhomogenous Poisson process; velocity estimation; Accuracy; Fluorescence; Imaging; Maximum likelihood estimation; Photonics; Trajectory; Cramer-Rao lower bound; maximum likelihood estimation; single molecule tracking;
Conference_Titel :
Optical MEMS and Nanophotonics (OMN), 2011 International Conference on
Conference_Location :
Istanbul
Print_ISBN :
978-1-4577-0334-8
DOI :
10.1109/OMEMS.2011.6031080
