Title :
Improvement of ischemic border zone with a newly developed mechanical cardiac assist device
Author :
Cui, T. ; Welkowitz, W. ; Li, John K.-J ; Petrucelli, S. ; Spotnitz, A. ; Mackenzi, J.
Author_Institution :
Dept. of Biomed. Eng., Rutgers Univ., Piscataway, NJ, USA
Abstract :
The effects of a mechanical cardiac assist device on the pressure-length loop of the left ventricle at the ischemic border zone were studied in six dogs following acute coronary occlusion. This device improved hemodynamic performance of the impaired heart by increasing myocardial contractility and decreasing ventricular preload. The experimental methods and results are presented
Keywords :
artificial organs; cardiology; haemodynamics; acute coronary occlusion; dogs; hemodynamic performance; ischemic border zone; left ventricle; mechanical cardiac assist device; myocardial contractility; pressure-length loop; ventricular preload; Actuators; Animals; Biomedical engineering; Cardiology; Clamps; Heart; Hemodynamics; Laboratories; Muscles; Myocardium;
Conference_Titel :
Bioengineering Conference, 1990., Proceedings of the 1990 Sixteenth Annual Northeast
Conference_Location :
State College, PA
DOI :
10.1109/NEBC.1990.66272
