Experimentally determining a parametric model for the point source response of a gamma camera (SPECT)

The authors experimentally investigate the response of a gamma camera to a source as a function of depth of the source in water and of distance from the gamma camera. They compute a least-squares estimate of the FWHM (full width at half maximum) of the camera line spread function as an affine function of these two parameters. They demonstrate a method for experimentally estimating the parameters of a camera response model and use this approach to estimate the parameters of a 2-D Gaussian model for the camera point source response in a true 3-D formulation. The 2-D Gaussian model was shown to yield good agreement with experimental data.<>