Title :
MEMS based multispectral confocal probe
Author :
Rattanavarin, S. ; Sarapukdee, P. ; Khemthongcharoen, N. ; Jarujareet, U. ; Jolivot, R. ; Jung, I.W. ; Lopez, D. ; Mandella, M.J. ; Piyawattanametha, Wibool
Author_Institution :
Nat. Electron. & Comput. Technol. Center (NECTEC), Pathumthani, Thailand
Abstract :
A MEMS based handheld multi-spectral confocal microscope has been developed as a noninvasive imaging instrument for cervical cancer screening. Tissue imaging depth of up to 400 μm was demonstrated. The maximum speed of image collection is up to 10 Hz with field of view (FOV) around 200×158 pixel2 size. Our handheld prototype is able to visualize cancer cells with cellular resolution (transverse resolution = 5 μm and axial resolution = 6 μm). Biological imaging demonstration was carried out on cell culture and tissues of human cervix.
Keywords :
bioMEMS; biological tissues; biomedical equipment; biomedical optical imaging; cancer; cellular biophysics; image resolution; optical microscopes; spectral analysis; MEMS based handheld multispectral confocal microscope; MEMS based multispectral confocal probe; biological imaging; cancer cell visualization; cell culture; cellular resolution; cervical cancer screening; field of view; handheld prototype; human cervix; image collection; noninvasive imaging instrument; tissue imaging; Cervical cancer; Image resolution; Micromechanical devices; Microscopy; Three-dimensional displays; Confocal; MEMS scanner; cervical cancer; dual-axis confocal; fluorescence;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII), 2013 Transducers & Eurosensors XXVII: The 17th International Conference on
Conference_Location :
Barcelona
DOI :
10.1109/Transducers.2013.6627233
