DocumentCode :
3462931
Title :
Maximum likelihood estimators for static and dynamic studies using emission tomography with auxiliary boundary information
Author :
Chiao, Ping-Chun ; Rogers, W. Leslie ; Hero, Alfred O. ; Clinthorne, Neal H.
Author_Institution :
Michigan Univ., Ann Arbor, MI, USA
fYear :
1991
fDate :
2-9 Nov. 1991
Firstpage :
1996
Abstract :
Maximum likelihood (ML) estimation methods were developed for static and dynamic studies using emission tomography (ET) with auxiliary boundary information. The estimators are developed through parameterizing object boundaries and introducing registration parameters so that optimal uses of auxiliary boundary information can be practically implemented. The estimators are region-of-interest (ROI)-based ML estimators and are developed by implementing an observation model generalized from one that has been commonly used in iterative reconstruction. The ML estimator was used to simulated dynamic myocardial perfusion studies, compare simulation results with a previously established Cramer-Rao lower bound, and demonstrate that the ML estimator is close to the C-R bound in performance. Simulation results suggest that ET projection data are inherently capable of aligning auxiliary boundary information. The present model-based ML estimation methods provide an efficient way to extract position information from ET data.<>
Keywords :
computerised tomography; radioisotope scanning and imaging; Cramer-Rao lower bound; auxiliary boundary information; dynamic studies; emission tomography; iterative reconstruction; maximum likelihood estimators; nuclear medicine; observation model; registration parameters; static studies; Computed tomography; Image reconstruction; Magnetic resonance imaging; Maximum likelihood estimation; Myocardium; Noise measurement; Nuclear measurements; Nuclear medicine; Parameter estimation; Surface fitting;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Nuclear Science Symposium and Medical Imaging Conference, 1991., Conference Record of the 1991 IEEE
Conference_Location :
Santa Fe, NM, USA
Print_ISBN :
0-7803-0513-2
Type :
conf
DOI :
10.1109/NSSMIC.1991.259266
Filename :
259266
Link To Document :
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