Title :
CMOS Mini Nuclear Magnetic Resonance System and its Application for Biomolecular Sensing
Author :
Liu, Yonh ; Sun, Nan ; Lee, Hakho ; Weissleder, Ralph ; Ham, Donhee
Author_Institution :
Harvard Univ., Cambridge, MA
Abstract :
This paper reports the smallest complete nuclear magnetic resonance (NMR) system made possible by CMOS integration of a highly sensitive and versatile RF transceiver. The system´s functionality is verified through proton NMR measurements in water and biomolecular sensing. The system is 60x more sensitive, 40x smaller, and 60x lighter than a commonly-used, state-of-the- art commercial benchtop NMR system.
Keywords :
CMOS integrated circuits; biomolecular electronics; biosensors; nuclear magnetic resonance; CMOS integration; RF transceiver; biomolecular sensing; nuclear magnetic resonance system; proton NMR measurements; Integrated circuit noise; Local oscillators; Magnetic field measurement; Magnetic switching; Magnetosphere; Nanoparticles; Nuclear magnetic resonance; RF signals; Radio frequency; Switches;
Conference_Titel :
Solid-State Circuits Conference, 2008. ISSCC 2008. Digest of Technical Papers. IEEE International
Conference_Location :
San Francisco, CA
Print_ISBN :
978-1-4244-2010-0
Electronic_ISBN :
978-1-4244-2011-7
DOI :
10.1109/ISSCC.2008.4523096
