SU-8 C-MEMS as candidate for long-term implantable pacemaker micro electrodes

Author

Grossenbacher, J. ; Gullo, M.R. ; Lecaude, S. ; Tevaearai Stahel, H. ; Brugger, J.

Author_Institution

Microsyst. Lab., EPFL, Lausanne, Switzerland

fYear

2015

fDate

21-25 June 2015

Firstpage

867

Lastpage

870

Abstract

This paper presents the first successful implantation of electrically conductive SU-8 C-MEMS electrodes able to pace muscle tissue in an animal model. The electrochemical characterizations of the ceramic electrodes show comparable values to state of the art platinum (Pt) metal electrodes. The micro-fabricated pacemaker electrodes were successfully tested in vitro (cardiomyocyte), in vivo (rat peripheral muscle) and ex vivo (explanted rat heart) pacing experiments. Short term C-MEMS implantation assays show lower levels of fibrosis compared to conventional electrodes.

Keywords

bioMEMS; biomedical electrodes; cardiology; ceramics; electrochemical electrodes; microelectrodes; microfabrication; muscle; pacemakers; platinum; C-MEMS implantation assays; Pt; animal model; art platinum metal electrodes; ceramic electrodes; electrical conductive SU-8 C-MEMS electrodes; electrochemical characterizations; ex vivo explanted rat heart; fibrosis; in vitro cardiomyocyte; in vivo rat peripheral muscle; long-term implantable pacemaker microelectrodes; microfabricated pacemaker electrodes; muscle tissue; Electric potential; Electrodes; Heart; In vivo; Metals; Muscles; Pacemakers; C-MEMS; SU-8; cell pacing; electrochemical analysis; fibrosis characterization; microfabrication; tissue pacing;

fLanguage

English

Publisher

ieee

Conference_Titel

Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), 2015 Transducers - 2015 18th International Conference on

Conference_Location

Anchorage, AK

Type

conf

DOI

10.1109/TRANSDUCERS.2015.7181061

Filename

7181061