Title :
Creating particulate microstructures for two- and three-dimensional cell patterning
Author :
Zhang, Xiaobing ; Zhao, Yiwen
Author_Institution :
Ohio State Univ., Columbus, OH, USA
Abstract :
This paper reports a unique method of fabricating microstructures made up of polymeric microparticles. By combining the technical power of both electrospray and microfabrication, particulate microstructures with controlled dimensions and spatial positions are created. Such structures have an immediate use in live cell patterning, where cells can be confined within desired regions on planar and curved surfaces, and in three-dimensional (3D) porous scaffolds. This study will help the development of parallel on-chip cell assays for miniaturized total analysis.
Keywords :
biomedical materials; cellular biophysics; materials preparation; microfabrication; polymers; porous materials; tissue engineering; curved surfaces; electrospray; microfabrication; parallel on-chip cell assays; particulate microstructures; planar surfaces; polymeric microparticles; three-dimensional cell patterning; three-dimensional porous scaffolds; two-dimensional cell patterning; Computer architecture; Electrodes; Microprocessors; Polymers; Substrates; Surface topography; Three-dimensional displays; Electrospray; cell patterning; polymeric microparticles; porous scaffold;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII), 2013 Transducers & Eurosensors XXVII: The 17th International Conference on
Conference_Location :
Barcelona
DOI :
10.1109/Transducers.2013.6627342
