Title : 
Bioluminescent bioreporter integrated circuit sensors for very low-level chemical detection
         
        
            Author : 
Islam, S.K. ; Qu, W. ; Vijayaraghvan, R. ; Terry, S.C. ; Zhang, M. ; Blalock, B. ; Caylor, S. ; Ripp, S. ; Sayler, G.S.
         
        
            Author_Institution : 
Dept. of Electr. & Comput. Eng., Tennessee Univ., Knoxville, TN
         
        
        
        
        
        
            Abstract : 
An integrated CMOS microluminometer for detection of very low-level bioluminescence is presented. Signal processing is accomplished with a current-to-frequency converter circuit. Photodiode, integrator, voltage reference circuit and noise are analyzed in detail in this paper. The biosensor chip was fabricated using a standard 0.35mum CMOS process and dissipate 3 mW for 3.3 V power supply. Test results are given to prove the concept
         
        
            Keywords : 
CMOS integrated circuits; bioluminescence; biosensors; chemical sensors; convertors; integrating circuits; photodiodes; reference circuits; 0.35 micron; 3 mW; 3.3 V; CMOS process; bioluminescent bioreporter integrated circuit sensors; biosensor chip; current-to-frequency converter circuit; integrated CMOS microluminometer; integrator; photodiode; signal processing; very low-level bioluminescence detection; very low-level chemical detection; voltage reference circuit; Bioluminescence; Biomedical signal processing; Biosensors; CMOS process; Chemical and biological sensors; Chemical sensors; Integrated circuit noise; Photodiodes; Power supplies; Voltage;
         
        
        
        
            Conference_Titel : 
Solid-State and Integrated Circuit Technology, 2006. ICSICT '06. 8th International Conference on
         
        
            Conference_Location : 
Shanghai
         
        
            Print_ISBN : 
1-4244-0160-7
         
        
            Electronic_ISBN : 
1-4244-0161-5
         
        
        
            DOI : 
10.1109/ICSICT.2006.306342