Modelling and Simulation of coronary circulation system

The paper presents a new numerical package for modelling and simulation of human circulatory system with an extension of coronary circulation model. The main aim of addition of the coronary model was to allow simulation and verification of the influence of the left ventricle assistance on the coronary flow conditions and the possibility of simulation of the coronary vessels occlusion. The whole package was implemented as a part of PExSim (Process Explorer and Simulation) application. As a result we have the useful tool, which gives an opportunity to study functions of individual components of the human circulatory system as well as the system as whole. It allows for simulation of proper and pathology circulation conditions, such as left or right heart failure. Implemented model of the ventricle assist device (VAD) gives the opportunity for modelling the influence of the heart assistance on the coronary flows and the imminent myocardial infarction conditions. Applied methods and the modelling data sets are presented. Analysis and comparison of the received results are included.