Title :
Skin adaptation: comparison of in vivo and in vitro results
Author :
Sanders, J.E. ; Hayes, C.L. ; Goldstein, B.S. ; Bell, D.M.
Author_Institution :
Washington Univ., Seattle, WA, USA
Abstract :
Electron microscopy differences between mechanically stressed skin and control skin were compared for an in vivo and an in vitro pig model. The in vivo model showed significant (p<0.01) collagen fibril increases at all dermal depths while the in vitro model demonstrated significant increases only in the deep dermis. Neither model showed scarred collagen fibril structures but instead natural skin architectures
Keywords :
biological techniques; biomechanics; electron microscopy; molecular biophysics; proteins; skin; collagen fibril; control skin; deep dermis; dermal depths; electron microscopy differences; in vitro pig model; in vivo pig model; mechanically stressed skin; natural skin architectures; scarred collagen fibril structures; skin adaptation; Biomedical engineering; Delta modulation; Dermis; Electron microscopy; In vitro; In vivo; Prosthetics; Shape measurement; Skin; Stress;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.802175
