Title :
Circuit design and verification for ultra low current sensing amplifier aimed at bio-sensor applications
Author :
Zhang, Lei ; He, Xiangqing ; Yu, Zhiqing
Author_Institution :
Inst. of Microelectron., Tsinghua Univ., Beijing
Abstract :
It has become increasingly apparent that ultra low current sensing amplifiers (LCSA) play a critical role in many sensor applications, especially for bio-sensing systems. The challenging tasks in LCSA design include achieving adequate performance in gain, noise, and stability, and the integration with sensor array on a single chip. In this paper, two CMOS LCSA circuits are described with current sensitivity in the range of pico-ampere. The detailed design considerations are discussed and simulated results which verify the design are presented
Keywords :
CMOS integrated circuits; amplifiers; biosensors; CMOS LCSA circuits; biosensor applications; circuit design; circuit verification; current sensitivity; ultra low current sensing amplifier; 1f noise; Biosensors; Circuit noise; Circuit simulation; Circuit stability; Circuit synthesis; Low-frequency noise; MOSFETs; Sensor arrays; Temperature distribution;
Conference_Titel :
ASIC, 2005. ASICON 2005. 6th International Conference On
Conference_Location :
Shanghai
Print_ISBN :
0-7803-9210-8
DOI :
10.1109/ICASIC.2005.1611353
