Title :
Leakage flow through mechanical prostheses: an initiator of platelet damage
Author :
Travis, Brandon R. ; Ellis, Jeffrey T. ; Marzec, U. ; Davoodi, Puya ; Momin, Takki ; Harker, Laurence ; Yoganathan, Ajit P.
Author_Institution :
Dept. of Chem. Eng., Georgia Inst. of Technol., Atlanta, GA, USA
Abstract :
The clinical histories of two bileaflet valves suggest that leakage flow could be an initiator of thromboembolic complications. To test this hypothesis, measurements of the flow field around bileaflet prostheses were combined with measurements of blood damage initiated by leakage flow through a prosthesis. The results of these studies show that leakage flow through bileaflet prostheses creates high Reynolds shear stresses and is responsible for platelet trauma
Keywords :
cardiology; haemodynamics; prosthetics; pulsatile flow; bileaflet prostheses; bileaflet valves; blood damage; flow field; high Reynolds shear stresses; hinge flow; leakage flow; leakage jets; mechanical prostheses; platelet damage initiator; platelet trauma; pulsatile flow conditions; thromboembolic complications; Blood; Chemical engineering; Chemical technology; Fasteners; Fluid flow measurement; Heart valves; History; Plasmas; Prosthetics; Stress;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.802224
