Leakage flow through mechanical prostheses: an initiator of platelet damage

Author

Travis, Brandon R. ; Ellis, Jeffrey T. ; Marzec, U. ; Davoodi, Puya ; Momin, Takki ; Harker, Laurence ; Yoganathan, Ajit P.

Author_Institution

Dept. of Chem. Eng., Georgia Inst. of Technol., Atlanta, GA, USA

Volume

1

fYear

1999

fDate

1999

Abstract

The clinical histories of two bileaflet valves suggest that leakage flow could be an initiator of thromboembolic complications. To test this hypothesis, measurements of the flow field around bileaflet prostheses were combined with measurements of blood damage initiated by leakage flow through a prosthesis. The results of these studies show that leakage flow through bileaflet prostheses creates high Reynolds shear stresses and is responsible for platelet trauma

Keywords

cardiology; haemodynamics; prosthetics; pulsatile flow; bileaflet prostheses; bileaflet valves; blood damage; flow field; high Reynolds shear stresses; hinge flow; leakage flow; leakage jets; mechanical prostheses; platelet damage initiator; platelet trauma; pulsatile flow conditions; thromboembolic complications; Blood; Chemical engineering; Chemical technology; Fasteners; Fluid flow measurement; Heart valves; History; Plasmas; Prosthetics; Stress;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.802224

Filename

802224