Title :
Double molecular tracer for myocardial regional flows
Author :
Matsumoto, T. ; Tachibana, H. ; Kajiya, F.
Author_Institution :
Dept. of Med. Eng., Kawasaki Med. Sch., Japan
Abstract :
The aim of this study was to establish a double tracer autoradiography for microregional myocardial flows. The two tracers, 3H and 125I-labeled desmethylimipramine, were efficiently extracted and well retained in myocardium. The accuracy of quantitation of tissue radioactivities was satisfactory. The present method will be useful in detecting the microregional flow changes in myocardium
Keywords :
blood flow measurement; cardiology; radioactive tracers; radioisotope imaging; 125I-labeled desmethylimipramine; 3H-labeled desmethylimipramine; double molecular tracer; double tracer autoradiography; microregional flow changes; microvascular level; myocardial regional flows; quantitation of tissue radioactivities; Artificial intelligence; Biomedical engineering; Calibration; Effluents; Fluid flow measurement; Heart; Image converters; Myocardium; Rabbits; Scintillation counters;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.802243
