Correlation between paced epimyocardial electrograms and stroke volume in heart transplants

Author

Kastner, P. ; Schreier, G. ; Schaffellner, S. ; Grasser, B. ; Iberer, F. ; Tscheliessnigg, K.H. ; Schaldach, M. ; Hutten, H.

Author_Institution

Inst. of Biomed. Eng., Tech. Univ. Graz, Austria

Volume

1

fYear

1999

fDate

1999

Abstract

In 10 heart transplant patients different hemodynamic states have been forced by randomized changes of pacing rate (PR) and postural variations (overall 40, 4±1 per patient). Cardiac output assessed with thermodilution technique was compared to the ventricular evoked response (VER) recorded with telemetric pacemakers from epimyocardial leads. Linear regression analysis between the negative extremum during the depolarization phase of the VER (R_amp) and the stroke volume (SV=CO/PR) resulted in the equation: R_amp[%]=140-0.4*SV[%] with r=0.89 and p<0.00001. This result confirms previously reported results of a distinct relation between the negative extremum of paced epimyocardial ECGs and geometrical variations of the heart

Keywords

electrocardiography; haemodynamics; pacemakers; surgery; cardiac output; depolarization phase; geometrical variations; graft rejection monitoring; heart transplants; hemodynamic states; linear regression analysis; negative extremum; paced epimyocardial electrograms; pacing rate; postural variations; randomized changes; stroke volume; telemetric pacemakers; thermodilution technique; ventricular evoked response; Aging; Biomedical engineering; Electrocardiography; Equations; Heart; Hemodynamics; Linear regression; Myocardium; Pacemakers; Telemetry;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.802245

Filename

802245