Title :
Multiple model predictive control of canine hemodynamic variables
Author :
Aufderheide, Brian ; Rao, Ramesh R. ; Bequette, B. Wayne
Author_Institution :
Dept. of Chem. Eng., Rensselaer Polytech. Inst., Troy, NY, USA
Abstract :
A multiple model predictive controller is designed to regulate mean arterial pressure, and cardiac output using inotropic and vasoactive drugs. The algorithm accounts for inter- and intra-patient variability and explicitly handles drug rate constraints. It is experimentally evaluated on canines that are pharmacologically altered to exhibit symptoms of hypertension and depressed cardiac output
Keywords :
biocontrol; haemodynamics; physiological models; predictive control; pressure control; algorithm; depressed cardiac output; hypertension; inotropic drugs; interpatient variability; intrapatient variability; mean arterial pressure regulation; pharmacologically altered canines; vasoactive drugs; Adaptive control; Anesthetic drugs; Blood pressure; Constraint optimization; Hemodynamics; Hypertension; Mercury (metals); Patient monitoring; Predictive control; Predictive models;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.802315
