Title :
Induction of LTP is associated with increased norepinephrine levels in the dentate gyrus of the freely moving rat
Author :
Bronzino, J.D. ; Kehoe, P. ; Hendriks, R. ; Roy, K. ; Fortin, D.F.
Author_Institution :
Dept. of Eng., Trinity Coll., Hartford, CT, USA
Abstract :
This paper presents (1) the simultaneous recording of microdialysis and electrophysiological measures from the dentate gyrus of freely moving rats, and (2) the correlation between the induction of LTP in the perforant path/dentate synapse of the awake male adult rat, with changes in hippocampal norepinephrine levels, which rose significantly during LTP induction
Keywords :
biochemistry; bioelectric phenomena; brain; neurophysiology; organic compounds; awake male adult rat; dentate gyrus; dentate synapse; electrophysiological measures; freely moving rat; increased norepinephrine levels; microdialysis; norepinephrine levels; perforant path; Animals; Brain; Educational institutions; Electrodes; Electrophysiology; Hippocampus; Monitoring; Probes; Rats; Surgery;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.802444
