Effects of repetitive transcranial magnetic stimulation on gene expression

Author

Ueno, Shoogo ; Fujiki, Minoru

Author_Institution

Dept. of Biomed. Eng., Tokyo Univ., Japan

Volume

1

fYear

1999

fDate

1999

Abstract

Although electroconvulsive seizure (ECS) has proven to be effective in the treatment of drug-resistant severe depression, the side effects following treatment (skull fracture, amnesia) have yet to be clarified. Repetitive transcranial magnetic stimulation (rTMS), however, is a less invasive method to treat central nervous systems diseases without the side effects accompanied with ECS. The consequences of high frequency repetitive transcranial magnetic stimulation (rTMS) on the gene expression of mice were evaluated. The pattern of glial fibrillary acidic protein (GFAP) upregulation was similar to that obtained following ECS

Keywords

biological effects of fields; biomagnetism; biomolecular effects of radiation; brain; diseases; genetics; health hazards; neurophysiology; proteins; amnesia; central nervous systems diseases; drug-resistant severe depression; electroconvulsive seizure; gene expression; glial fibrillary acidic protein upregulation; high frequency repetitive transcranial magnetic stimulation; less invasive method; mice; side effects; skull fracture; Biomedical engineering; Central nervous system; Coils; Diseases; Gene expression; Humans; Magnetic stimulation; Medical treatment; Mice; Proteins;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.802548

Filename

802548