Title :
Effects of repetitive transcranial magnetic stimulation on gene expression
Author :
Ueno, Shoogo ; Fujiki, Minoru
Author_Institution :
Dept. of Biomed. Eng., Tokyo Univ., Japan
Abstract :
Although electroconvulsive seizure (ECS) has proven to be effective in the treatment of drug-resistant severe depression, the side effects following treatment (skull fracture, amnesia) have yet to be clarified. Repetitive transcranial magnetic stimulation (rTMS), however, is a less invasive method to treat central nervous systems diseases without the side effects accompanied with ECS. The consequences of high frequency repetitive transcranial magnetic stimulation (rTMS) on the gene expression of mice were evaluated. The pattern of glial fibrillary acidic protein (GFAP) upregulation was similar to that obtained following ECS
Keywords :
biological effects of fields; biomagnetism; biomolecular effects of radiation; brain; diseases; genetics; health hazards; neurophysiology; proteins; amnesia; central nervous systems diseases; drug-resistant severe depression; electroconvulsive seizure; gene expression; glial fibrillary acidic protein upregulation; high frequency repetitive transcranial magnetic stimulation; less invasive method; mice; side effects; skull fracture; Biomedical engineering; Central nervous system; Coils; Diseases; Gene expression; Humans; Magnetic stimulation; Medical treatment; Mice; Proteins;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.802548
