Dose dependent inhibition of bone loss by low level, high frequency mechanical loading of the lower appendicular and axial skeleton of post-menopausal women

Author

McLeod, K. ; Ryaby, J. ; Cullen, D. ; Recker, R. ; Rubin, C.

Author_Institution

Program in Biomed. Eng., State Univ. of New York, Stony Brook, NY, USA

Volume

1

fYear

1999

fDate

1999

Abstract

Correlation of changes in bone mineral density in the human lumbar spine, femoral neck and greater trochanter, against total duration of exposure to a 30 Hz, 0.2 g mechanical loading over a one year period (range of 2000-9000 seconds), demonstrates a strong positive relationship between treatment duration and inhibition of bone loss (p<0.05). These results suggest the lack of a saturation response in skeletal tissue for low level dynamic mechanical loading

Keywords

biomechanics; gynaecology; orthopaedics; patient treatment; 1 y; 2000 to 9000 s; 30 Hz; axial skeleton; bone mineral density changes correlation; dose dependent bone loss inhibition; low level dynamic mechanical loading; low level high frequency mechanical loading; lower appendicular skeleton; post-menopausal women; saturation response; treatment duration; Biomedical engineering; Bone tissue; Frequency; Humans; In vivo; Minerals; Muscles; Neck; Skeleton; Spine;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.802578

Filename

802578