Development of a sarcomere model using hardware

We are developing a hardware model of sarcomere dynamics to obtain a better understanding of how groups of sarcomeres interact to produce macroscopic muscle behaviors. Both the computational complexity of the sarcomeres and muscle´s highly parallel nature have limited previous attempts to model muscle at the level of crossbridge dynamics. Real-time models of muscle structure and dynamics can be implemented, however, using very large-scale integrated circuits, which share muscle´s computational complexity and parallelism. This paper addresses the mathematical models that will underlie the implementation of such a crossbridge-level, hardware model of sarcomere dynamics