An investigation of N-let summation mechanisms in muscle

Author

Dorgan, Stephen J.

Author_Institution

Inst. of Autom. Control Eng., Tech. Univ. of Munich, Germany

Volume

1

fYear

1999

fDate

1999

Abstract

The dynamics responsible for non-linear (N-let) force summation effects in mammalian skeletal muscle are investigated. These investigations are performed using a recently developed physiologically based mathematical model for skeletal muscle. Simulation results are compared to both internal and external experimental data from isolated muscles and muscle fibres. The results indicate that a subtle interplay between the Ca²⁺ release and contraction dynamics of muscle may be responsible for N-let summation effects

Keywords

biocontrol; biomechanics; force control; muscle; nonlinear dynamical systems; physiological models; Ca²⁺ release; FNS; N-let control strategies; N-let summation mechanisms; complex I/O dynamics; contraction dynamics; external data; internal data; isolated muscles; mammalian skeletal muscle; muscle fibres; muscle force generation; nonlinear force summation effects; physiologically based mathematical model; rabbit muscle; Automatic control; Fatigue; Force control; Immune system; Mathematical model; Muscles; Nonlinear dynamical systems; Predictive models; Pulse generation; Strontium;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.802631

Filename

802631