Title :
Effect of transdermal energy on drug´s permeability flux
Author :
Jiali, Bao ; Qiaohong, Hu ; Wenquan, Lang ; Jianqing, Gao ; Ping, Wu
Author_Institution :
Biomed. Eng. Inst., Zhejiang Univ., Hangzhou, China
Abstract :
The effect of transdermal energy on the fluxes of Tetracaini Hydrochlordum (TH) and Naproxenum is studied to explore the low voltage electroporative technique. The results show that: (1) the drug´s transdermal energy will create a saturation; (2) the F/E value declines as time extends; and (3) the effect of electroporation is concerned with energy and the drug´s characteristics
Keywords :
biodiffusion; bioelectric phenomena; drug delivery systems; skin; Naproxenum; Tetracaini Hydrochlordum; drug permeability flux; low voltage electroporative technique; saturation; transdermal energy; Biomedical engineering; Blindness; Drug delivery; Electric resistance; Immune system; Iron; Low voltage; Optimal control; Predictive models; Skin;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.804012
