Title :
MarSelHR: A Haplotype Reconstruction System Using Linkage Disequilibrium
Author :
Yeo, Sang-Soo ; Kim, Sung Kwon
Author_Institution :
Dept. of Comput. Sci. & Commun. Eng., Kyushu Univ., Fukuoka
Abstract :
We propose MarSelHR, a haplotype reconstruction system, which is a combination of LD based block partitioning with Clark´s algorithm. MarSelHR uses less CPU processing time than other haplotype reconstruction systems, and makes possible large-scale data processing using less memory through block unit processing. Furthermore, MarSelHR involves biological meaning through LD based partitioning and is able to result in more precise inference.
Keywords :
biology computing; genetics; Marselarge-scale data processing LHR; block partitioning; haplotype reconstruction system; large-scale data processing; linkage disequilibrium; Biology computing; Costs; Couplings; Data processing; Humans; Inference algorithms; Information technology; Large-scale systems; Partitioning algorithms; Skin;
Conference_Titel :
Frontiers in the Convergence of Bioscience and Information Technologies, 2007. FBIT 2007
Conference_Location :
Jeju City
Print_ISBN :
978-0-7695-2999-8
DOI :
10.1109/FBIT.2007.142
