Title :
Complement activation and SEM studies of membrane oxygenators
Author :
Lautier, A. ; Sargentini, J.C. ; Dehe, T.
Author_Institution :
INSERM, Creteil, France
Abstract :
Four devices (one bubbler and three membrane oxygenating devices) have been developed for extracorporeal circulation (ECC) for coronary bypass or valvular replacement. Determinations of C3, C4, C5, and C3a, C4a, C5a have been made during the course of ten ECC applications. Indexes have been defined to evaluate the activation of the complement system in order to compare the devices. Scanning electron microscopy (SEM) studies on the membranes after the ECC show that membrane oxygenators are more haemocompatible than bubblers.<>
Keywords :
artificial organs; membranes; scanning electron microscope examination of materials; artificial organ; bubbler; complement activation; coronary bypass; extracorporeal circulation; haemocompatibility; membrane oxygenators; scanning electron microscopy; valvular replacement;
Conference_Titel :
Engineering in Medicine and Biology Society, 1988. Proceedings of the Annual International Conference of the IEEE
Conference_Location :
New Orleans, LA, USA
Print_ISBN :
0-7803-0785-2
DOI :
10.1109/IEMBS.1988.94962
