DocumentCode :
3491545
Title :
Finding optimal control policy by using dynamic programming in conjunction with state reduction
Author :
Chen, Xi ; Ching, Wai-Ki
Author_Institution :
Dept. of Math., Univ. of Hong Kong, Hong Kong, China
fYear :
2011
fDate :
2-4 Sept. 2011
Firstpage :
274
Lastpage :
278
Abstract :
In this paper we study the problem of finding optimal control policy for probabilistic Boolean networks (PBNs). Previous works have been done by using dynamic programming-based (DP) method. However, due to the high computational complexity of PBNs, DP method is computationally inefficient for large networks. Inspired by the state reduction strategies studied in [10], we consider using dynamic programming in conjunction with state reduction approach to reduce the computational cost of DP method. Numerical examples are given to demonstrate the efficiency of our proposed method.
Keywords :
Boolean functions; bioinformatics; biological techniques; biomedical engineering; cellular biophysics; complex networks; dynamic programming; genetics; medical computing; molecular biophysics; probability; PBN; dynamic programming; gene regulatory network; optimal control policy; probabilistic Boolean networks; state reduction approach; Boolean functions; Complexity theory; Conferences; Dynamic programming; Heuristic algorithms; Optimal control; Probabilistic logic;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Systems Biology (ISB), 2011 IEEE International Conference on
Conference_Location :
Zhuhai
Print_ISBN :
978-1-4577-1661-4
Electronic_ISBN :
978-1-4577-1665-2
Type :
conf
DOI :
10.1109/ISB.2011.6033165
Filename :
6033165
Link To Document :
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