An in-vitro test system for electrochemical sensors

Author

Heller, James ; McMahan, William ; Bryan, Nancy

Author_Institution

Eli Lilly & Co., Indianapolis, IN, USA

fYear

1988

fDate

4-7 Nov. 1988

Firstpage

795

Abstract

A computer system has been developed to automate the in-vivo evaluation of amperometric electrochemical sensors in unanesthetized, tethered rabbits. Subcutaneous glucose, oxygen and temperature are monitored. Continuous, simultaneous monitoring of eight animals for several weeks is possible. Data collection rates are adjustable up to once every five minutes. Blood sample withdrawal and intravenous injection are carried out manually through a remote access port with computer prompting. Blood chemistry results are entered via keyboard and merged with the database from the sensor outputs. This multiple, parallel testing with minimal personnel intervention has made in-vivo statistical analysis of experimental electrochemical sensors feasible.<>

Keywords

biological techniques and instruments; detectors; electrochemical analysis; O/sub 2/; blood chemistry; blood sample withdrawal; computer system; data collection rate; electrochemical sensors; in vivo test system; intravenous injection; statistical analysis; subcutaneous glucose; temperature; unanaesthetised tethered rabbits;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1988. Proceedings of the Annual International Conference of the IEEE

Conference_Location

New Orleans, LA, USA

Print_ISBN

0-7803-0785-2

Type

conf

DOI

10.1109/IEMBS.1988.95047

Filename

95047