Title :
Real-time measurement of cardiac stroke volume using Compton backscattered X-rays
Author :
Herr, M. ; McInerney, J. ; Moore, R. ; Musch, T.
Author_Institution :
Pennsylvania State Univ., University Park, PA, USA
Abstract :
A technique which uses Compton backscattered X-rays to provide real-time measurements of stroke volume and cardiac output in the isolated working rat heart preparation is presented. A basic system was assembled and tested on mechanical models. Six isolated rat hearts were studied. Preliminary work shows that this X-ray backscatter detection system responds in a highly linear fashion and can detect rapid (>4 Hz) and small amplitude (<0.1 ml) changes in volume in the isolated and perfused rat heart. The amplitudes of the dynamic backscatter waveforms generally correlate well with directly measured stroke volumes and cardiac output
Keywords :
Compton effect; X-ray applications; biological techniques and instruments; cardiology; haemodynamics; physiological models; Compton backscattered X-rays; X-ray backscatter detection system; cardiac output; cardiac stroke volume; dynamic backscatter waveforms; isolated working rat heart; mechanical models; perfused rat heart; real-time measurements; Backscatter; Electromagnetic scattering; Heart; Low pass filters; Particle scattering; Solid scintillation detectors; Volume measurement; X-ray detection; X-ray detectors; X-ray scattering;
Conference_Titel :
Bioengineering Conference, 1990., Proceedings of the 1990 Sixteenth Annual Northeast
Conference_Location :
State College, PA
DOI :
10.1109/NEBC.1990.66291