Change in strain image contrast with applied compression evaluated via finite elements analysis

Finite elements analysis (FEA) simulations showed that small strain shear modulus and the nonlinear behavior play roles in the changes of image contrast as the material deforms. The clinical relevance of this work is that nonlinear elasticity of the object being imaged may not only affect the image quality during strain imaging but might also provide information that can be used to differentiate tissues based on their nonlinear behaviors.