A ppb level, miniaturized fast response amperometric nitric oxide sensor for asthma diagnostics

Author

Gatty, H.K. ; Leijonmarck, S. ; Antelius, Mikael ; Stemme, Goran ; Roxhed, Niclas

Author_Institution

Micro & Nanosyst, KTH R. Inst. of Technol., Stockholm, Sweden

fYear

2013

fDate

20-24 Jan. 2013

Firstpage

1001

Lastpage

1004

Abstract

This paper reports on a novel miniaturized MEMS-based amperometric nitric oxide sensor that is suitable for a point of care testing device for asthma. The novelty lies in the combination of a high surface area microporous structured electrode, nano-structured Nafion that is coated on the side walls of the micropores, and liquid electrolyte. This combination allows detection of very low concentration (parts-per-billion) gas, has a high sensitivity of 4 μA/ppm/cm² and has both a response and a recovery time of 6 s. The sensor is integrated with a PCB potentiostat to form a complete measuring module. The limit of detection of this sensor was estimated to be 0.3 ppb.

Keywords

amperometric sensors; bioMEMS; diseases; electrochemical electrodes; electrolytes; nitrogen compounds; NO; PCB potentiostat; asthma diagnostics; high surface area microporous structured electrode; liquid electrolyte; miniaturized fast response amperometric nitric oxide sensor; nanostructured Nafion; novel miniaturized MEMS-based amperometric nitric oxide sensor; point of care testing device; time 6 s; Electric potential; Electrodes; Platinum; Radiation detectors; Sensitivity; Silicon;

fLanguage

English

Publisher

ieee

Conference_Titel

Micro Electro Mechanical Systems (MEMS), 2013 IEEE 26th International Conference on

Conference_Location

Taipei

ISSN

1084-6999

Print_ISBN

978-1-4673-5654-1

Type

conf

DOI

10.1109/MEMSYS.2013.6474416

Filename

6474416