• DocumentCode
    3500001
  • Title

    Spira Mirabilis enhanced density gradient centrifguation

  • Author

    Kearney, S.M. ; Kinahan, D.J. ; Ducree, J.

  • Author_Institution
    Nat. Centre for Sensor Res., Dublin City Univ., Dublin, Ireland
  • fYear
    2013
  • fDate
    20-24 Jan. 2013
  • Firstpage
    1041
  • Lastpage
    1044
  • Abstract
    The centrifugal microfluidic “lab-on-a-disc” paradigm is particularly suited to the pre-conditioning of whole blood. In this work we define the geometry of sedimentation chambers using the Spira Mirabilis (equiangular spiral) and so enhance the Boycott Effect and increase the speed at which blood may be stratified using a density gradient media. We find that using the Spira Mirabilis defined chambers can increase the speed of stratification by up to 25% compared with equivalent linear chambers.
  • Keywords
    bioMEMS; blood; lab-on-a-chip; microfluidics; sedimentation; Spira Mirabilis defined chambers; Spira Mirabilis enhanced density gradient centrifguation; blood preconditioning; boycott effect; centrifugal microfluidic lab-on-a-disc paradigm; density gradient media; equiangular spiral; sedimentation chambers; Blood; Educational institutions; Media; Microfluidics; Rotation measurement; Sediments; Spirals;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Micro Electro Mechanical Systems (MEMS), 2013 IEEE 26th International Conference on
  • Conference_Location
    Taipei
  • ISSN
    1084-6999
  • Print_ISBN
    978-1-4673-5654-1
  • Type

    conf

  • DOI
    10.1109/MEMSYS.2013.6474427
  • Filename
    6474427